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  • ÇÐÁ¦°£¿¬±¸ | Interdisciplinary Studies in Gambling | Î¥学Ρ研ϼ

    date : 2015-05-20 01:10|hit : 1903
    Article] Neuropsychological frontal impairments and negative symptoms in schizophrenia
    DocNo of ILP: 4172

    Doc. Type: Article

    Title: Neuropsychological frontal impairments and negative symptoms in schizophrenia

    Authors: Martino, DJ; Bucay, D; Butman, JT; Allegri, RF

    Full Name of Authors: Martino, Diego J.; Bucay, Demian; Butman, Judith T.; Allegri, Ricardo F.

    Keywords by Author: theory of mind; decision making; gambling

    Keywords Plus: PREFRONTAL CORTICAL DYSFUNCTION; 1ST EPISODE SCHIZOPHRENIA; MIND; CORTEX; APATHY; PERFORMANCE; DEFICITS; PEOPLE; BRAIN; SPECTRUM

    Abstract: Negative symptoms have been associated with frontal lobe dysfunction in schizophrenia. However, neuropsychological studies that evaluated the correlation between performance in tests sensitive to the dorsolateral prefrontal cortex (DLPFC) and negative symptoms have shown inconsistent results. Growing evidence has appeared that not only the DLPFC but other prefrontal regions could be involved in schizophrenia. We evaluated schizophrenic patients and healthy controls using three "frontal tests": the Wisconsin Card Sorting Test (WCST), the Iowa Gambling Task (GT) and a Theory of Mind test (Faux Pas), and studied the relationship between performance in these tests and negative symptomatology. Schizophrenic patients had worse performance than normal controls on the WCST, GT and Faux Pas test. The severity of the negative symptoms showed a moderate to high correlation with performance in the Faux Pas test. Our findings support the idea that different prefrontal regions could be affected in people with schizophrenia and that the damage to each of these regions could be, at least in part, independent of the damage to the others. Some negative symptoms could be associated with frontal medial cortex dysfunction. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

    Cate of OECD: Clinical medicine

    Year of Publication: 2007

    Business Area: gamble

    Detail Business: gamble

    Country: Ireland

    Study Area: regulation, control, mind theory, mind theory, patient, decision, schizo-obsessive

    Name of Journal: PSYCHIATRY RESEARCH

    Language: English

    Country of Authors: AREA Res & Dev Mental Hlth, RA-1425 Buenos Aires, DF, Argentina; Alvear Psychiat Hosp GCBA, Buenos Aires, DF, Argentina; Zubizarreta Hosp GCBA, Memory Res Lab, Buenos Aires, DF, Argentina; Consejo Nacl Invest Cient & Tecn, Natl Res Council, RA-1033 Buenos Aires, DF, Argentina

    Press Adress: Martino, DJ (reprint author), AREA Res & Dev Mental Hlth, Gurruchaga 2463,1 C, RA-1425 Buenos Aires, DF, Argentina.

    Email Address: diejmartino@yahoo.com.ar

    Citaion:

    Funding:

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    Number of Citaion: 54

    Publication: ELSEVIER IRELAND LTD

    City of Publication: CLARE

    Address of Publication: ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND

    ISSN: 0165-1781

    29-Character Source Abbreviation: PSYCHIAT RES

    ISO Source Abbreviation: Psychiatry Res.

    Volume: 152

    Version: 41673

    Start of File: 121

    End of File: 128

    DOI: 10.1016/j.psychres.2006.03.002

    Number of Pages: 8

    Web of Science Category: Psychiatry

    Subject Category: Psychiatry

    Document Delivery Number: 208QH

    Unique Article Identifier: WOS:000249333800004

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