학제간연구 | Interdisciplinary Studies in Gambling | 跨学科研究
- date : 2015-05-20 01:10|hit : 1887
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- Review] Glanders: off to the races with Burkholderia mallei
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DocNo of ILP: 4043
Doc. Type: Review
Title: Glanders: off to the races with Burkholderia mallei
Authors: Whitlock, GC; Estes, DM; Torres, AG
Full Name of Authors: Whitlock, Gregory C.; Estes, D. Mark; Torres, Alfredo G.
Keywords by Author: Burkholderia; Burkholderia mallei; glanders; virulence factors; immune responses
Keywords Plus: MAJOR VIRULENCE DETERMINANT; AEROSOL CHALLENGE; EPITHELIAL-CELLS; BALB/C MICE; SUBTRACTIVE HYBRIDIZATION; INTRACELLULAR SURVIVAL; MURINE MODEL; IV PILIN; IN-VIVO; PSEUDOMALLEI
Abstract: Burkholderia mallei, the etiologic agent of the disease known as glanders, is primarily a disease affecting horses and is transmitted to humans by direct contact with infected animals. The use of B. mallei as a biological weapon has been reported and currently, there is no vaccine available for either humans or animals. Despite the history and highly infective nature of B. mallei, as well as its potential use as a bio-weapon, B. mallei research to understand the pathogenesis and the host responses to infection remains limited. Therefore, this minireview will focus on current efforts to elucidate B. mallei virulence, the associated host immune responses elicited during infection and discuss the feasibility of vaccine development.
Cate of OECD: Biological sciences
Year of Publication: 2007
Business Area: other
Detail Business: medicine & science
Country: England
Study Area: review, review, older, response, disease
Name of Journal: FEMS MICROBIOLOGY LETTERS
Language: English
Country of Authors: Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA; Univ Texas Med Branch, Dept Pediat, Galveston, TX 77555 USA; Univ Texas Med Branch, Sealy Ctr Vaccine Dev, Galveston, TX 77555 USA; Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 USA
Press Adress: Torres, AG (reprint author), Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA.
Email Address: altorres@utmb.edu
Citaion:
Funding:
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Number of Citaion: 48
Publication: BLACKWELL PUBLISHING
City of Publication: OXFORD
Address of Publication: 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
ISSN: 0378-1097
29-Character Source Abbreviation: FEMS MICROBIOL LETT
ISO Source Abbreviation: FEMS Microbiol. Lett.
Volume: 277
Version: 2
Start of File: 115
End of File: 122
DOI: 10.1111/j.1574-6968.2007.00949.x
Number of Pages: 8
Web of Science Category: Microbiology
Subject Category: Microbiology
Document Delivery Number: 234UV
Unique Article Identifier: WOS:000251190400001
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