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- Article] Health-related quality of life - An introduction
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DocNo of ILP: 4039
Doc. Type: Article
Title: Health-related quality of life - An introduction
Authors: Khanna, D; Tsevat, J
Full Name of Authors: Khanna, Dinesh; Tsevat, Joel
Keywords by Author:
Keywords Plus: RHEUMATOID-ARTHRITIS; IMPORTANT DIFFERENCE; PSYCHOMETRIC PROPERTIES; ASSESSMENT WHOQOL; CLINICAL-TRIALS; SF-36; ORGANIZATION; PREFERENCES; UTILITIES; STATES
Abstract: Chronic diseases often have a relapsing and remitting course with substantial impact on function and quality of life. Rheumatoid arthri(RA) is considered a chronic, inflammatory autoimmune disorder that causes disabling and painful inflammation in the joints that can lead to detrimental effects on health-related quality of life (HRQOL). This article provides an overview of HRQOL and a comprehensive description of the attributes of different instruments to measure it. A wide variety of instruments have been created to measure HRQOL using 2 approaches: health status and health utility. Commonly used generic health status instruments in RA are the Medical Outcomes Study 36-Item Short Form (SF-36) and the Health Assessment Questionnaire Disability Index. Health utility measures are divided into 2 categories, direct and indirect. The most common direct health utility measures are the standard gamble, time to trade-off, and rating scale, while the most commonly used indirect measures are EuroQOL, SF-6D, and the Health Utility Index. Different applications of the instruments are analyzed in this article, including their utility to estimate burden of disease, as end points in clinical trials, and to monitor outcomes in clinical practice, as well as their uses in public policy and in individual decision making.
Cate of OECD: Health sciences
Year of Publication: 2007
Business Area: other
Detail Business: medicine & science
Country: India
Study Area: culture, quality of life, utility, utility, clinical trial, clinical trial, preference, disease
Name of Journal: AMERICAN JOURNAL OF MANAGED CARE
Language: English
Country of Authors: [Khanna, Dinesh] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Rheumatol, Los Angeles, CA 90095 USA; [Tsevat, Joel] Univ Cincinnati, Coll Med, Ctr Clin & Translat Sci & Training,Inst Study Hlt, Dept Internal Med,Ctr Clin Effectiveness, Cincinnati, OH USA; [Tsevat, Joel] Vet Healthcare Syst Ohio, Res & Dev, Hlth Serv, Cincinnati, OH USA
Press Adress: Khanna, D (reprint author), Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Rheumatol, 1000 Vet Ave,Rm 32-59 Rehabil Bldg, Los Angeles, CA 90095 USA.
Email Address: dkhanna@mednet.ucla.edu
Citaion:
Funding:
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Number of Citaion: 39
Publication: AMER MED PUBLISHING, M W C COMPANY
City of Publication: JAMESBURG
Address of Publication: 241 FORSGATE DR, STE 102, JAMESBURG, NJ 08831 USA
ISSN: 1088-0224
29-Character Source Abbreviation: AM J MANAG CARE
ISO Source Abbreviation: Am. J. Manag. Care
Volume: 13
Version: 9
Start of File: S218
End of File: S223
DOI:
Number of Pages: 6
Web of Science Category: Health Care Sciences & Services; Health Policy & Services; Medicine, General & Internal
Subject Category: Health Care Sciences & Services; General & Internal Medicine
Document Delivery Number: 249FV
Unique Article Identifier: WOS:000252213900002
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