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- Article] Impulsivity is associated with behavioral decision-making deficits
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DocNo of ILP: 3872
Doc. Type: Article
Title: Impulsivity is associated with behavioral decision-making deficits
Authors: Franken, IHA; van Strien, JW; Nijs, I; Muris, P
Full Name of Authors: Franken, Ingmar H. A.; van Strien, Jan W.; Nijs, Ilse; Muris, Peter
Keywords by Author: reversal learning; decision-making; impulsivity; frontal functions; reward
Keywords Plus: SOMATIC MARKER HYPOTHESIS; IOWA GAMBLING TASK; PREFRONTAL CORTEX; ORBITOFRONTAL CORTEX; DRUG-ADDICTION; SUBSTANCE USE; REVERSAL; DISORDERS; REWARD; DAMAGE
Abstract: Impaired decision-making is a key-feature of many neuropsychiatric disorders. In the present Study, we examined task performance in a healthy population consisting of those whose scores indicated high and low impulsivity on several behavioral decision-making tasks reflecting orbitofrontal functioning. The measures included tasks that assess decision-making with and without a learning component and choice flexibility. The results show that Subjects high on impulsivity display an overall deficit in their decision-making performance as compared with subjects low on impulsivity. More specifically, subjects with high impulsivity show weaknesses in learning of reward and Punishment associations in order to make appropriate decisions (reversal-learning task and Iowa Gambling Task), and impaired adaptation of choice behavior according to changes in Stimulus-reward contingencies (reversal-learning task). simple, non-learning, components of reward- and punishment-based decision-making (Rogers Decision-Making Task) seem to be relatively unaffected. Above all, the results indicate that impulsivity is associated with a decreased ability to alter choice behavior in response to fluctuations in reward contingency. The findings add further evidence to the notion that trait impulsivity is associated with decision-making, a function of the orbitofrontal cortex. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
Cate of OECD: Clinical medicine
Year of Publication: 2008
Business Area: gamble
Detail Business: gamble
Country: Ireland
Study Area: impulse, drug
Name of Journal: PSYCHIATRY RESEARCH
Language: English
Country of Authors: [Franken, Ingmar H. A.; van Strien, Jan W.; Nijs, Ilse; Muris, Peter] Erasmus Univ, Inst Psychol, Erasmus Affect Neurosci Lab, NL-3000 DR Rotterdam, Netherlands
Press Adress: Franken, IHA (reprint author), Erasmus Univ, Inst Psychol, Erasmus Affect Neurosci Lab, Woudestein T12-35,POB 1738, NL-3000 DR Rotterdam, Netherlands.
Email Address: franken@fsw.eur.nl
Citaion: Van Strien, Jan/0000-0002-3198-9267
Funding:
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Number of Citaion: 60
Publication: ELSEVIER IRELAND LTD
City of Publication: CLARE
Address of Publication: ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND
ISSN: 0165-1781
29-Character Source Abbreviation: PSYCHIAT RES
ISO Source Abbreviation: Psychiatry Res.
Volume: 158
Version: 2
Start of File: 155
End of File: 163
DOI: 10.1016/j.psychres.2007.06.002
Number of Pages: 9
Web of Science Category: Psychiatry
Subject Category: Psychiatry
Document Delivery Number: 287JO
Unique Article Identifier: WOS:000254913600006
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