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- Article] Behavioral and neural correlates of loss aversion and risk avoidance in adolescents and adults
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DocNo of ILP: 928
Doc. Type: Article
Title: Behavioral and neural correlates of loss aversion and risk avoidance in adolescents and adults
Authors: Barkley-Levenson, EE; Van Leijenhorst, L; Galvan, A
Full Name of Authors: Barkley-Levenson, Emily E.; Van Leijenhorst, Linda; Galvan, Adriana
Keywords by Author: Loss aversion; Risk; Decision-making; Adolescence; Development; fMRI
Keywords Plus: DECISION-MAKING; ORBITOFRONTAL CORTEX; BRAIN ACTIVATION; AGE-DIFFERENCES; PROSPECT-THEORY; REWARD; CHILDREN; CHOICES; REPRESENTATION; PERSPECTIVE
Abstract: Individuals are frequently faced with risky decisions involving the potential for both gain and loss. Exploring the role of both potential gains and potential losses in predicting risk taking is critical to understanding how adolescents and adults make the choice to engage in or avoid a real-life risk. This study aimed to examine the impact of potential losses as well as gains on adolescent decisions during risky choice in a laboratory task. Adolescent (n=18) and adult (n=16) participants underwent functional magnetic resonance imaging (fMRI) during a mixed gambles task, and completed questionnaires measuring real-world risk-taking behaviors. While potential loss had a significantly greater effect on choice than potential gain in both adolescents and adults and there were no behavioral group differences on the task, adolescents recruited significantly more frontostriatal circuitry than adults when choosing to reject a gamble. During risk-seeking behavior, adolescent activation in medial prefrontal cortex (mPFC) was negatively correlated with self-reported likelihood of risk taking. During risk-avoidant behavior, mPFC activation of in adults was negatively correlated with self-reported benefits of risk-taking. Taken together, these findings reflect different neural patterns during risk-taking and risk-avoidant behaviors in adolescents and adults. (C) 2012 Elsevier Ltd. All rights reserved.
Cate of OECD: Basic medicine
Year of Publication: 2013
Business Area: gamble
Detail Business: gamble
Country: England
Study Area: development, development, correlationperspective theory, correlation, perspective theory, adolescent, behavior, risk
Name of Journal: DEVELOPMENTAL COGNITIVE NEUROSCIENCE
Language: English
Country of Authors: [Barkley-Levenson, Emily E.; Van Leijenhorst, Linda; Galvan, Adriana] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90095 USA; [Galvan, Adriana] Univ Calif Los Angeles, Brain Res Inst, Los Angeles, CA 90095 USA
Press Adress: Galvan, A (reprint author), Univ Calif Los Angeles, Dept Psychol, 1285 Franz Hall,Box 951563, Los Angeles, CA 90095 USA.
Email Address: ebarkley@ucla.edu; lleijenhorst@fsw.leidenuniv.nl; agalvan@ucla.edu
Citaion:
Funding: UCLA Pre-Doctoral Training Program in the Translational Neuroscience of Drug Abuse; Rubicon grant from the Netherlands Organization for Scientific Research (NWO)
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Number of Citaion: 45
Publication: ELSEVIER SCI LTD
City of Publication: OXFORD
Address of Publication: THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
ISSN: 1878-9293
29-Character Source Abbreviation: DEV COGN NEUROS-NETH
ISO Source Abbreviation: Dev. Cogn. Neurosci.
Volume: 3
Version:
Start of File: 72
End of File: 83
DOI: 10.1016/j.dcn.2012.09.007
Number of Pages: 12
Web of Science Category: Neurosciences
Subject Category: Neurosciences & Neurology
Document Delivery Number: 095EU
Unique Article Identifier: WOS:000315318300009
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