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- Article] Analysis of risk factors for the development of equine protozoal myeloencephalitis in horses
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DocNo of ILP: 6664
Doc. Type: Article
Title: Analysis of risk factors for the development of equine protozoal myeloencephalitis in horses
Authors: Saville, WJ; Reed, SM; Morley, PS; Granstrom, DE; Kohn, CW; Hinchcliff, KW; Wittum, TE
Full Name of Authors: Saville, WJ; Reed, SM; Morley, PS; Granstrom, DE; Kohn, CW; Hinchcliff, KW; Wittum, TE
Keywords by Author:
Keywords Plus: OPOSSUM DIDELPHIS-VIRGINIANA; SARCOCYSTIS-NEURONA; CEREBROSPINAL-FLUID; STRESS; IMMUNITY; VACCINE; MICE; HOST
Abstract: Objective-To investigate risk factors for development of equine protozoal myeloencephalitis (EPM) in horses. Design-Case control study. Animals-251 horses admitted to The Ohio State University Veterinary Teaching Hospital from 1992 to 1995. Procedure-On the basis of clinical signs of neurologic disease and detection of antibody to Sarcocystis neurona or S neurona DNA in cerebrospinal fluid, a diagnosis of EPM was made for 251 horses. Two contemporaneous series of control horses were selected from horses admitted to the hospital. One control series (n = 225) consisted of horses with diseases of the neurologic system other than EPM (neurologic control horses), and the other consisted of 251 horses admitted for reasons other than nervous system diseases (nonneurologic control horses). Data were obtained from hospital records and telephone conversations. Risk factors associated with disease status were analyzed, using multivariable logistic regression. Results-Horses ranged from 1 day to 30 years old (mean +/- SD, 5.7 +/- 5.2 years). Risk factors associated with an increased risk of developing EPM included age, season of admission, prior diagnosis of EPM on the premises, opossums on premises, health events prior to admission, and racing or showing as a primary use. Factors associated with a reduced risk of developing EPM included protection of feed from wildlife and proximity of a creek or river to the premises where the horse resided. Conclusions and Clinical Relevance-Development of EPM was associated with a number of management-related factors that can be altered to decrease the risk for the disease.
Cate of OECD: Veterinary science
Year of Publication: 2000
Business Area: other
Detail Business: medicine & science
Country: USA
Study Area:
Name of Journal: JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
Language: English
Country of Authors: Ohio State Univ, Coll Vet Med, Dept Vet Prevent Med, Columbus, OH 43210 USA; Ohio State Univ, Coll Vet Med, Dept Vet Clin Sci, Columbus, OH 43210 USA; Amer Vet Med Assoc, Schaumburg, IL 60173 USA
Press Adress: Saville, WJ (reprint author), Ohio State Univ, Coll Vet Med, Dept Vet Prevent Med, Columbus, OH 43210 USA.
Email Address:
Citaion:
Funding:
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Number of Citaion: 43
Publication: AMER VETERINARY MEDICAL ASSOC
City of Publication: SCHAUMBURG
Address of Publication: 1931 N MEACHAM RD SUITE 100, SCHAUMBURG, IL 60173-4360 USA
ISSN: 0003-1488
29-Character Source Abbreviation: J AM VET MED ASSOC
ISO Source Abbreviation: J. Am. Vet. Med. Assoc.
Volume: 217
Version: 8
Start of File: 1174
End of File: 1180
DOI: 10.2460/javma.2000.217.1174
Number of Pages: 7
Web of Science Category: Veterinary Sciences
Subject Category: Veterinary Sciences
Document Delivery Number: 363EN
Unique Article Identifier: WOS:000089822300019
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