위험관리 | Cases and Studies of Risk Management in Lottery & Gambling | 危險管理
- date : 2015-05-20 01:10|hit : 1978
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- Article] Risk-attitude and patient treatment preferences
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DocNo of ILP: 6098
Doc. Type: Article
Title: Risk-attitude and patient treatment preferences
Authors: Fraenkel, L; Bogardus, ST; Wittink, DR
Full Name of Authors: Fraenkel, L; Bogardus, ST; Wittink, DR
Keywords by Author: lupus nephritis; patient preferences; risk-attitude
Keywords Plus: LUPUS NEPHRITIS; IMMUNOSUPPRESSIVE DRUGS; RHEUMATOID-ARTHRITIS; CONJOINT-ANALYSIS; DECISION-MAKING; GRAPHIC DATA; INFORMATION; PREDNISONE; PHYSICIANS; DISEASE
Abstract: Women's treatment preferences for lupus nephritis vary widely even after adjusting for sociodemographic factors and disease severity. Attitude toward risk may partially explain interpatient variability in treatment preference. The objective of this study was to examine the association between `risk-attitude',and patient treatment preferences in lupus nephritis. Sixty-five premenopausal women with systemic lupus erythematosus were interviewed. Patient preferences for cyclophosphamide versus azathioprine for the treatment of lupus nephritis were ascertained using an Adaptive Conjoint Analysis questionnaire. Risk-attitude was ascertained by asking patients to choose between a pair of lotteries having the same expected value but differing in spread ( the difference between the worst and best outcomes). Respondents preferring the wider spread were classified as relatively more risk-seeking and those preferring the narrower spread were classified as relatively more risk-averse. Twenty-eight percent of respondents were classified as relatively more risk-seeking. Risk-seeking women were more likely to prefer cyclophosphamide for the treatment of lupus nephritis compared with risk-averse women [ least square mean ( SD) preference for cyclophosphamide 63 3 among risk-seeking women versus 55 2 among risk-averse women ( P < 0.03)]. The association between risk attitude and treatment preference persisted as the probabilities of adverse events were varied to reflect the range of risks reported in the literature. Our results suggest that patients' relative risk-attitudes, as measured by a lottery task, are related to their treatment preferences. Differences in risk-attitude may help explain the inter-patient variability in treatment preferences.
Cate of OECD: Clinical medicine
Year of Publication: 2003
Business Area: other
Detail Business: medicine & science
Country: England
Study Area: interviewprobability, interview, probability, patient, attitude, drug, disease
Name of Journal: LUPUS
Language: English
Country of Authors: VA Connecticut Hlth Care Syst, West Haven, CT 06516 USA; Yale Univ, Dept Med, New Haven, CT 06520 USA; Yale Univ, Sch Management, New Haven, CT 06520 USA
Press Adress: Fraenkel, L (reprint author), Yale Univ, Dept Internal Med, Rheumatol Sect, POB 208031,333 Cedar St, New Haven, CT 06520 USA.
Email Address:
Citaion:
Funding:
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Number of Citaion: 37
Publication: ARNOLD, HODDER HEADLINE PLC
City of Publication: LONDON
Address of Publication: 338 EUSTON ROAD, LONDON NW1 3BH, ENGLAND
ISSN: 0961-2033
29-Character Source Abbreviation: LUPUS
ISO Source Abbreviation: Lupus
Volume: 12
Version: 5
Start of File: 370
End of File: 376
DOI: 10.1191/0961203303lu371oa
Number of Pages: 7
Web of Science Category: Rheumatology
Subject Category: Rheumatology
Document Delivery Number: 678RD
Unique Article Identifier: WOS:000182879500004
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