심리적도박 | Cases and Studies in Pathological Gambling | 游戏设计
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- Article] Clinical correlates of pathological gambling symptoms in patients with epilepsy
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DocNo of ILP: 3691
Doc. Type: Article
Title: Clinical correlates of pathological gambling symptoms in patients with epilepsy
Authors: Cavanna, AE; Mula, M; Strigaro, G; Servo, S; Tota, G; Barbagli, D; Collimedaglia, L; Viana, M; Cantello, R; Monaco, F
Full Name of Authors: Cavanna, Andrea E.; Mula, Marco; Strigaro, Gionata; Servo, Serena; Tota, Grazia; Barbagli, Davide; Collimedaglia, Laura; Viana, Michele; Cantello, Roberto; Monaco, Francesco
Keywords by Author: epilepsy; pathological gambling; obsessionality; G-SAS; temporal lobe epilepsy
Keywords Plus: TEMPORAL-LOBE EPILEPSY; OBSESSIVE-COMPULSIVE DISORDER; PSYCHIATRIC COMORBIDITY; SPECTRUM DISORDERS; PREVALENCE; ASSOCIATION; AGONISTS; DISEASE
Abstract: Pathological gambling symptoms (PGS), that is, the subjective urge to gamble and the actual gambling behaviors, are currently acknowledged as relatively common symptoms among Western countries, with an estimated point prevalence of 0.6-1.1% in the general population. Converging evidence suggests that PGS are overrepresented in patients with neurological conditions affecting dopaminergic reward pathways, and can be expressed in both impulse control disorders and obsessive-compulsive spectrum disorders. This study explored the clinical correlates of PGS in patients with epilepsy. Eighty-eight consecutive adult outpatients recruited at three epilepsy clinics in northern Italy were assessed using the Gambling-Symptom Assessment Scale (G-SAS), along with a battery of psychometric instruments to index depression (Beck Depression Inventory [BDI]), anxiety (Spielberger State-Trait Anxiety Inventory [STAI]), and obsessionality (Yale-Brown Obsessive Compulsive Scale [YBOCS]) symptoms. On the G-SAS, patients with a diagnosis of temporal lobe epilepsy (TLE) reported a mean [sd] G-SAS score of 2.0 [5.7], significantly higher than patients with frontal lobe epilepsy (FLE) (0.6 [1.7]) and idiopathic generalized epilepsy (IGE) (0.4 [1.4]). Moreover, multiple regression analysis showed that G-SAS scores were selectively predicted by YBOCS scores, thus suggesting an association between the expression of obsessional spectrum symptoms and PGS in patients with TLE. Alterations in the mesolimbic reward system could represent the putative neuropathological substrate for this multifaceted clinical picture.
Cate of OECD: Clinical medicine
Year of Publication: 2008
Business Area: gamble
Detail Business: gamble
Country: USA
Study Area:
Name of Journal: EPILEPSIA
Language: English
Country of Authors: [Cavanna, Andrea E.] Inst Neurol, Dept Neuropsychiat, London WC1N 3BG, England; [Cavanna, Andrea E.; Mula, Marco; Strigaro, Gionata; Servo, Serena; Tota, Grazia; Barbagli, Davide; Collimedaglia, Laura; Viana, Michele; Cantello, Roberto; Monaco, Francesco] Amedeo Avogadro Univ, Dept Neurol, Novara, Italy; [Mula, Marco] Univ Pisa, Dept Psychiat, Pisa, Italy; [Tota, Grazia] S Andrea Hosp, Div Neurol, Vercelli, Italy; [Barbagli, Davide] Infermi Hosp, Div Neurol, Biella, Italy
Press Adress: Cavanna, AE (reprint author), Inst Neurol, Dept Neuropsychiat, Queen Sq, London WC1N 3BG, England.
Email Address: A.Cavanna@ion.ucl.ac.uk
Citaion: Viana, Michele/0000-0003-4356-8109
Funding:
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Number of Citaion: 29
Publication: WILEY-BLACKWELL
City of Publication: HOBOKEN
Address of Publication: 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
ISSN: 0013-9580
29-Character Source Abbreviation: EPILEPSIA
ISO Source Abbreviation: Epilepsia
Volume: 49
Version: 8
Start of File: 1460
End of File: 1464
DOI: 10.1111/j.1528-1167.2008.01586.x
Number of Pages: 5
Web of Science Category: Clinical Neurology
Subject Category: Neurosciences & Neurology
Document Delivery Number: 331BS
Unique Article Identifier: WOS:000257988300020
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