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- Article] Pilot Study to Test the Effectiveness of Different Financial Incentives to Improve Medication Adherence
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DocNo of ILP : 12084
Document Type : Article
Document Title : Pilot Study to Test the Effectiveness of Different Financial Incentives to Improve Medication Adherence
Authors : Garza, KB; Owensby, JK; Lloyd, KB; Wood, EA; Hansen, RA
Author Full Name : Garza, Kimberly B.; Owensby, Justin K.; Lloyd, Kimberly Braxton; Wood, Elizabeth A.; Hansen, Richard A.
Author Keywords : adherence; cardiovascular drugs; clinical trial design; hyperlipidennia; hypertension
Keywords Plus? : RANDOMIZED-CONTROLLED-TRIAL; THERAPY; PATIENT; CHOICE
Abstract : Background: Medication nonadherence affects health care costs, morbidity, and mortality. Concepts from behavioral economics can guide the development of interventions to improve medication adherence. Objective: To measure the relative effectiveness of 2 behavioral economic-based incentive structures to improve medication adherence. Methods: This randomized controlled trial compared adherence among participants taking antihypertensive or antihyperlipidemic medications randomized to usual care (UC), guaranteed pay-out (GPO) incentives, or lottery incentives. Daily adherence was measured over a 90-day period using electronic caps (Medication Event Monitoring System [MEMS]). The GPO group received $30 up-front in a virtual account, with $0.50 deducted for each missed dose. Lottery group participants were eligible for a weekly $50 drawing, but only if they had taken their medication as prescribed all week. An electronic survey assessed self-reported adherence. Statistical analysis included descriptive statistics, paired t tests, ANOVA, and Pearson's correlations. Results: In all, 36 participants were randomized (UC, n = 11; GPO, n = 14; lottery, n = 11). Mean percentage (+/- SD) of days adherent during the incentive period was highest in the lottery group (96% +/- 5%), followed by the GPO group (94% +/- 9%) and the UC group (94% +/- 9%). There were no statistically significant differences among groups (P > 0.05). MEMS-measured adherence was not significantly correlated with a patient's self-reported adherence (P > 0.05) at baseline but was correlated at 90-day follow-up (P < 0.001). Conclusions: Although no statistically significant differences in adherence were demonstrated in this small sample of highly adherent participants, larger studies in a more diverse population or with other medications might show otherwise.
Web of Science Categories : Pharmacology & Pharmacy
Year Published : 2016
Publisher : SAGE PUBLICATIONS INC
Publisher City : THOUSAND OAKS
Language : English
Cited Reference Count : 30
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